Alka-Seltzer, an antacid and pain reliever was first launched in 1931 on March 19 by Dr. Miles Medicine Company. One of the famous ad campaigns for this product was “Plop, plop, fizz, fizz, Oh What a Relief it Is,” an ad created by The Good Wife’s father. Hmmm, i.e. Julianna Margulies’ father Paul Margulies, who was an ad executive in New York.